For the first time, doctors have utilized a gene-editing therapy tailored to a baby born with a rare, life-threatening genetic disorder. The treatment involved infusing billions of microscopic gene editors to target and repair a specific mutation in the baby’s liver. Early results indicate the therapy has at least partially reversed the condition, potentially preventing…
Chinese scientist He Jiankui, who previously sparked global controversy by creating the first gene-edited babies, is now focusing on using gene-editing to combat Alzheimer’s disease. His new research involves testing a genetic mutation that could potentially protect against dementia, starting with trials on mice. Despite his past ethical breaches, He is committed to adhering to…
Yale scientists have developed a new CRISPR tool, CRISPR-Cas12a, which allows for more seamless gene editing and the simultaneous assessment of multiple genetic changes. This advancement enables researchers to study complex genetic interactions and their effects on various diseases, including cancer. The new tool also facilitates the rapid generation of disease and treatment models, offering…
The article discusses Evo 2, the largest generative AI model for biology, developed by scientists at the Arc Institute, Stanford University, and Nvidia. Trained on 128,000 genomes, Evo 2 can write whole chromosomes and small genomes from scratch. It also analyzes DNA mutations affecting proteins, RNA, and overall health, particularly in non-coding regions linked to…